Pleioflow – Cleanroom
Project Description Construction of Cleanroom with purity class ISO 7 (at operation) according to ISO 14644 for the company Pleioflow,
Cleanrooms
BCT group is specialized in cleanroom design, construction and validation. We also hold international certification in Cleanroom Technology & Cleanrooms Validation Process from Cleanrooms Testing and Certification Board – international.
Layout Design
Flow Determination
We develop cleanrooms for euGMP Pharmaceutical Applications (GRADE A,B,C,D), for electronic applications (ISO 3 – ISO 8), for aseptic food packaging (ISO 5) or for medical or micro devices manufacturing
Design scope:
Total Compliance with GMP Standards and ISO 14644
Zero cross-contamination RISK
Sustainability, minimum energy footprint, LEAN Operation
Expenditure optimization (CAPEX & OPEX)
Happy to share
our expertise!
Cleanroom Structural Part
Cleanroom Build
Rooms construction with a variety of materials all compliant with GMP requirements
Special finishes, modular ceiling systems, interlocks, LAFs etc developed and produced by V. Bougatsos SA
Clean Design Concept
Separate Materials & Personnel Flow
Rooms Overpressure from cleaner to less clean
Differential Pressures for cross-contamination elimination
Cleanroom HVAC Systems
HVAC systems is the heart of engineering in Cleanroom Applications and determine the success of a Cleanroom. Cleanroom HVAC aims to:
Provide the necessary air achieving the required Classification
Maintain constant Temperature and relative Humidity
Achieve Differential Pressures and Pressure Cascades
Safeguards cross-contamination avoidance
Constant trouble-free operation and energy conservation is of central consideration in Cleanroom to HVAC design.
Successful design of Cleanroom HVAC system requires deep knowledge of thermodynamics, psychometrics, fluid dynamics, HVAC controls and incorporation of systems communication protocols and machine learning.
As most of the new production plans aim to high efficiency, uniform quality, elimination of production interruptions and continuous compliance to standards owners persist in effective Cleanroom HVAC design.
Old practices are substituted by new technologies based on more precise controlling, effective monitoring and energy conservation technics.
BCT as an engineering solution developing company with an extended background in industrial engineering is able to provide the most suitable design for each Cleanroom Application.
Cleanroom Validation
Cleanroom Validation – Testing – Certification Elaboration of All test according to ISO 14644
All test are performed in order to assure:
Correct Air volumes
Differential pressures maintenance
Integrity of HEPA Filters
Efficient Air Flow by air flow visualization
Room Recovery
Achieved Cleanliness Class in compliance with ISO 14644 and GMP
Constant Temperature & Relative Humidity
Cleanroom other Mechanical systems
Delivering a turn-key cleanroom often involves a series of other mechanical systems which BCT is capable to design and provide accordingly.
Such systems are:
Environment Monitoring Systems (EMS - FMS)
Production equipment electrical supply
Compressed air Systems
Dedusting systems
Steam, Hot and Cold water for the Production Equipment needs
Laboratory gases (CO2, N2, O2)
Purify Water and Extra Purifying water
Data management from production equipment
Relevant Projects
ES Systems – Cleanroom
Cleanroom class ISO 7 Design & Construction for ES Systems company in Koropi, Attica.It will be used as a laboratory
Adelco – Cleanroom
Life Science Athens 2019-2021 Reconstruction of Production Areas, Packaging Suite and Warehouses of Adelco SA Total reconstruction completed in three
